Unlikelly, but incase of problems deleting the gamedata is a "must do" to try to find the problem, also the trophies and savedata, as explained here:
http://www.psx-place.com/threads/ar-tonelico-qogaknell-of-ar-ciel.20886/
The gamedata needs to be deleted first because the files are generated by the game, so by deleting them you dont lose anything, at the next boot of the game the gamedata will be generated again
Next (if deleting gamedata doesnt works), and just incase... you can delete the game trophies installation, manually (by using a filemanager)... maybe the problem is happening because the game is trying to unlock a trophy for "congratulations, you spent more than 10 hours playing, bronze trophy", and the game crashes at that point because the trophies installation is partially corrupted
And the last resort... is to delete the savedata too, this sucks because usually you have stored some game progress in the savedata, but before deleting it you can make a copy of the folder (just incase you want to restore it incase the cause of the problem is not the savegame)
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Anyway... if the problem only happens in one game (but all others works fine), then the problem is in the game !
So additionally to the tests im mentioning deleting files generated by the game (gamedata, trophies, and savedata in that order) you should also download the IRD file of the game and run a check to the game files
Most probably the game files are going to match with the IRD, but just incase is needed to verify it because maybe some of the game files went corrupt
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Also, if the game is stored in a external USB storage device (hdd, flash, whatever) defragment it
And to defragment the internal PS3 hdd enter in "recovery menu" and use the option "Restore filesystem"
if the game continues crashing after all this checks... your PS3 is bewitched